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Microbiota-targeted therapy is an emerging potential strategy for SLE treatment, but it needs to overcome three core issues: safety, feasibility, and regulation

The report of the Institute of Medicine (IOM) of the United States in 2011 not only discussed the upper limits (ULs) of the intake of high-dose vitamin D preparations during acute and short-term administration within a limited time period, but also emphasized the long-term administration of vitamin D