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the preferred method of oral administration employs an uptake mechanism that differs from GSH administered using prior methods, as well as most other thiol compounds

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Recent efforts by Lim and colleagues, aimed to elucidate mixed-pathology interactions by using a transgenic plus viral-mediated gene delivery approach, whereby they injected adult Line 61 (hThy1-syn) mice with AAV-tau, hTau mice with AAV-syn, and APP/PS1 mice with AAV-syn

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f-g , Single-cell clones were established from the polyclonal population, and GGT activity (f) (n = 3 technical replicates from 2 independent experiments) and cell numbers (g) (n = 6 technical replicates for Control or n = 4 technical replicates for Cys 2 -free + GSH from 2 independent experiments) for cells grown in control (208 M cystine