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Trends Genet 31:140149 Villar-Cheda B, Meijide AD, Joglar B, Perez AIR, Guerra MJ, Labandeira-Garcia JL (2012) Involvement of microglial RhoA/RhoKinase pathway activation in the dopaminergic neuron death

Octocrylene's safety profile is generally quite good, though a review study in Contact Dermatitis reports an "increasing number of patients with photo contact allergy to octocrylene." Mainly adults with ketoprofen-sensitivity and children with sensitive skin are affected, so if you have a small kid, it is probably better to use octocrylene-free sunscreens