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An innovative NRF2 nano-modulator induces lung cancer ferroptosis and elicits an immunostimulatory tumor microenvironment

(110) showed that endogenously generated NO and ROS contribute to HIF-1 accumulation by inhibiting prolyl hydroxylase domain proteins (PHDs) via S-nitrosation of PHD2, thus preventing HIF-1 degradation during hypoxia (110)

B.et al (2007)

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To summarize the research results, melanin preparations from black cumin and black sesame seeds can be used as natural antioxidants in the process of encapsulation of flaxseed oil