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As suggested by Petr et al

Fluoride and Chlorine: Often found in municipal water supplies

1.1.4 Growth factors FBS stimulates cell division and promotes cell cycle progression by offering various growth factors, such as epidermal growth factors (EGFs), fibroblast growth factors (FGFs), insulin-like growth factors (IGFs), transforming growth factors (TGFs) and platelet-derived growth factor (PDGF) (Lee et al., 2023)