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It has been reported that inhibiting diacylglycerol acyltransferase 2 (DGAT2), an enzyme in the LD biogenesis process, by PF-06424439 reduced LD content, inhibited cell migration, and sensitized MCF7 breast cancer cells to radiation [170]

Epigenetics in the vascular endothelium

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Therefore, we speculated that ferroptosis is also involved in ph-IOP-induced glaucomatous RGC loss, and this involvement is closely regulated by iron metabolism