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Then in a 2009 study, Beneficial effects of a Cannabis sativa extract treatment on diabetesinduced neuropathy and oxidative stress (Phytotherapy Research, Wiley Online Library, Nov 2009) found that in rats with induced diabetes, Cannabis sativa decreased glutathione (one of our bodies naturally produced and most effective antioxidants, also known as the master antioxidant) loss in the liver while preventing nerve damage
Glutathione is the most important redox regulator that controls inflammatory processes, thus damaging the periodontium [28]
Disclosures: Khurram Jamil: Mallinckrodt Pharmaceuticals: Employee, Galectin Therapeutics: Stock - publicly traded company, Galectin Therapeutics: Employee, Naim Alkhouri: Madrigal: Grant/Research Support, Madrigal: Speaking and Teaching, Novo Nordisk: Consulting, Novo Nordisk: Grant/Research Support, Gilead: Grant/Research Support, Corcept: Grant/Research Support, Boehringer Ingelheim: Grant/Research Support, Echosens: Speaking and Teaching, Perspectum: Consultant, Cima: Consultant, Fibronostics: Consultant, 89Bio: Grant/Research Support, Inventiva: Grant/Research Support, Merck: Grant/Research Support, Pfizer: Grant/Research Support, Ipsen: Speaking and Teaching, Intercept: Speaking and Teaching, Madrigal: Consulting, Research Funding, Novo Nordisk: Consulting, Research Funding, Inventiva: Research Funding, Boehringer Ingelheim: Consulting, Research Funding, Corcept: Research Funding, Ipsen: Consulting, Research Funding, Gliead: Consulting, Research Funding, Speaking, Perspectum: Consulting, Research Funding, Cima: Advisor, 89Bio: Consulting, Research Funding, Akero: Grant/Research Support, Mitchell Shiffman: Bio89: Grant/Research Support, CymaBay: Advisor, CymaBay: Grant/Research Support, Durect: Grant/Research Support, Galectin: Grant/Research Support, Genentech: Grant/Research Support, Genentech: Speaking and Teaching, Gilead: Grant/Research Support, Gilead: Advisor, Gilead: Speaking and Teaching, HepQuant: Grant/Research Support, HepQuant: Advisor, Hamni: Grant/Research Support, High Tide: Grant/Research Support, Interept: Grant/Research Support, Interecept: Speaking and Teaching, Intercept: Advisor, Intra-Sana: Advisor, Intra-Sana: Speaking and Teaching, Ipsen: Advisor, Ipsen: Grant/Research Support, Ipsen: Speaking and Teaching, Madrigal: Grant/Research Support, Madrigal: Speaking and Teaching, Mirum: Grant/Research Support, Pliant: Grant/Research Support, Salix: Grant/Research Support, Salix: Advisor, Viking: Grant/Research Support, Hesham Elgouhari: Nothing to Disclose, Eric Lawitz: Nothing to Disclose, Edward Mena: Nothing to Disclose, Raj Vuppalanchi: Nothing to Disclose, CHIRAG PATEL: Nothing to Disclose, Seth Zuckerman: Galectin Therapeutics: Employee, Pol Boudes: Galectin Therapeutics, Inc.: Employee 2136 A MULTI-SCALE COMPUTATIONAL MODEL OF THE HEPATIC CIRCULATION APPLIED TO PREDICT THE PORTAL PRESSURE AFTER TRANSJUGULAR INTRAHEPATIC PORTOSYSTEMIC SHUNT (TIPS) Yang Ling 1 Jiaqi Gu 2 Yi Xiang 3 Jitao Wang 3 Deqiang Ma 4 He Zhu 5 Tianyu Liu 6 Chunlong Li 7 Qi Zhang 3 Jiahao Han 3 Deping Ding 4 Wei Wang 5 Qianlong Li 6 Haoguang Wan 7 Tianqi Wang 8 Xiaolong Qi 3 , 1 Zhongda Hospital, Southeast University, 2 School of Medicine, Southeast University, 3 Zhongda Hospital, 4 Taihe Hospital, 5 The Sixth People's Hospital of Shenyang, 6 Suining Central Hospital, 7 The Six Affiliated Hospital of Nantong U, 8 Gongli Hospital Medical Technology Background: Transjugular intrahepatic portosystemic shunt (TIPS) is a widely used surgery for patients with portal hypertension
Oral administration is typically preferred for gut-specific goals, though injectable can address both gut and systemic inflammation simultaneously
