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Wang R, Chen C, Liu W, Zhou T, Xun P, He K, Chen P

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As in the case of many chronic degenerative diseases, increased production of reactive oxygen species has been considered to play an important role, even in the pathogenesis of chronic fluoride toxicity

For glucose starvation, media with normal glucose level were removed, cells washed twice with 1X PBS, and glucose-deprived media (final glucose level at 0.5 mM) with or without lactic acid added for 12 h

NAD is a crucial coenzyme for supporting healthy cellular energy and adrenal function