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sinensis (Li et al., 2001c)

Retrieved 14 December 2025

3.3 Regulation of immune responses A central mechanism by which probiotics ameliorate UC is the restoration of intestinal immune homeostasis through multidimensional, systems-level modulation of host immunity

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Interestingly, GSAAT(WT), GSAAT(C138S) and GSAAT(C396S) lines were still markedly redox responsive, and exhibited up to 20% higher enzyme activity when supplied with DTT relative to the UT control conditions, while the two gsa2 lines expressing GSAAT(C168S) and GSAAT(C190S) resulted only in 9% and 2% increased GSAAT activity upon addition of DTT to the extracts ( Supplementary Figure 3E )