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However, this model has certain limitations: it only stays in the early stage of ALD and only causes mild increases in serum Alanine aminotransferase (ALT), aspartate aminotransferase (AST) and mild steatosis, which limits its wide application (Tien et al

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Identification of novel CD44v6-binding peptides that block CD44v6 and deliver a pro-apoptotic peptide to tumors to inhibit tumor growth and metastasis in mice

Other Nrf2-dependent genes, including GPX4, GSH and NADPH synthesis genes, as well as epigenetic regulators of lipid hydroperoxides, contribute to its ferroptosis-inhibitory effects (117119)

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