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Ipamorelin, also believed by its experimental identifier NNC 26-0161, is a pentapeptide characterized by the amino acid sequence Aib-His-D-2-Nal-D-Phe-Lys-NH, which also interacts with the pituitary gland cells but via a different mechanism

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The researchers included 31 randomized, controlled trials (RCTs) that administered hGH for 2-52 weeks to participants without GHD aged 50 or older

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Overlapping pathways might amplify side effects or suppress natural hormone function

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Research Square Preprint2022 Jan

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