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The study found that treated animals demonstrated significantly faster functional research applications, improved tendon mechanical strength, and better organized collagen fibers compared to control groups

L.LeoniS.OhnishiT.et al

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The latter binds to RAGE, leading to an increase in NF-B-dependent pro-inflammatory gene expression, suggesting that CML-S100A8/S100A9 generated in inflammatory lesions can elicit a RAGE-dependent inflammatory response (129)