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It also notes that the SOP lacks defined timeframes for patient notification and investigation following OOS events

Early studies have demonstrated that staurosporine, a non-selective inhibitor of kinases and well-known inducer of apoptosis, as well as serum deprivation dont trigger cell death in mature erythrocytes [181]

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Inhibiting their biosynthesis can weaken fungal virulence, making PP-IP metabolic pathways potential targets for antifungal drug development (Kang, 2018)