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Although pain has never been considered a primary symptom of PD, several researchers, including Charcot 17 , had already referred to painful aspects of the disease: Sometimes Parkinson's is preceded by neuralgic or rheumatoid pains, which are occasionally of great intensity, being located in the extremity (...) that will soon be affected (...) by the convulsive agitation

1 Introduction Cancer is a disease caused by the abnormal proliferation of cells, leading to uncontrollable cell growth and the formation of primary solid tumors which can invade adjacent and distant sites, a process known as cancer metastasis (Fares et al., 2020

Three-dimensional high-frequency backscatter and envelope quantification of cancerous human lymph nodes

It also activates the PI3K/PKB/Akt pathway, influencing cell functions [10-11]

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