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8 This was the first trial in patients with a first acute demyelinating event (now, clinically isolated syndrome) to show efficacy in delaying time-to-clinically definite MS and was recognized as a significant medical advance as it introduced the concept of early treatment and led to revisions in diagnostic criteria for MS

Supplementing with B12 may help mitigate the fatigue and lethargy commonly associated with hangovers

This delayed impulse originates in the atrioventricular (AV) node and then proceeds through the His-Purkinje network, which encompasses the bundle of HIS, the left and right bundle branches, and the Purkinje fibers (10)

References Dharmarajan TS, Norkus EP: Approaches to vitamin B12 deficiency

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