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CJC-1295 poses a risk of immunogenicity, a condition in which your body reacts to a protein-based drug as though it were a pathogen.9 In such an event, youd get none of the benefits that CJC-1295 would otherwise offer and could instead suffer a life-threatening allergic response.21 The best way to avoid serious adverse events related to immunogenicity is to undergo a comprehensive medical assessment with a licensed provider knowledgeable in therapeutic peptides and their potential hazards

However: Avoid stacking MK-677 with injectable secretagogues this is usually redundant and may increase side effects

Thyroid follicular cells themselves can aberrantly express MHC class II and co-stimulatory molecules (B7.1/CD80), enabling them to act as non-professional antigen-presenting cells (APCs) and amplify the autoimmune cascade

BMC Surg