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For best results, use consistently for a minimum of 3 months

doi:10.1186/s13045-020-00990-3 9

In vivo direct reprogramming of reactive glial cells into functional neurons after brain injury and in an Alzheimers disease model

improvement of MDS-UPDRS total score by 37.5 % at 52 weeks), but patients in the prasinezumab group had significantly slower motor and non-motor symptom progression and improvement in imaging biomarkers consistent with disease modifying effect (Prothena Corporation 2020)