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Today, AOD-9604 remains a topic of scientific interest, not as an approved therapy, but as a case study in how translational challenges can derail promising preclinical results

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the failure of these treatments to restore function and slow functional disease progression can be traced to their inability to correct the underlying cause of the dysfunction- diminished synaptic connectivity among neurons in the striatum and neuronal loss in the substantia nigra (SN)

Contraindications (4), Dosing and Administration (2.4), Drug Interactions (7.1), Patient Counseling Information (17), and Warnings and Precautions (5.5) have been updated to include additional contraindication for recent alcohol use (i.e

Possible side effects may include fatigue, headache, or stomach discomfort