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Shi L, Linville MC, Tucker EW, Sonntag WE, Brunso-Bechtold JK

doi: 10.1038/s41598-018-29371-0 274 JiangWHanYLiangTZhangCGaoFHouG

The initial loading dose phase is crucial here, providing that quick surge of B12 to help address the neurological effects

PAEC ferroptosis induces HMGB1 release, upregulates macrophage TLR4 expression and activates the NLRP3 inflammasome in vitro Inflammation plays an important role in the pathogenesis of PH 50