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Specifically, these fucoidans have been found to mitigate the reduction in protein levels of the antioxidant enzyme GPX4, offering partial protection against erastin-induced oxidative stress and ferroptosis in ARPE-19 cells ( 3.2.5 Vitamin A metabolites Vitamin A, also known as retinol, is a fat-soluble vitamin that serves as a precursor for various bioactive substances, including retinaldehyde (retinal) and different forms of retinoic acid ( 3.3 Pharmacodynamic elements from traditional Chinese medicine 3.3.1 Puerarin Puerarin (C21H20O9), a natural isoflavone derived from Pueraria lobata and utilized in traditional Chinese herbal medicine, has been proven to possess preventive properties against iron overload (Song et al., 2020)

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Brenner N, Mentzer AJ, Butt J, Michel A, Prager K, Brozy J, et al

At present, cisplatin nephrotoxicity can be effectively prevented by hydration

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