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Furthermore, current potential therapeutic strategies targeting inflammatory pathways are reviewed, including anti-inflammatory agents (e.g., cyclooxygenase-2 (COX-2) and NLRP3 inhibitors), antioxidants (such as N-acetylcysteine (NAC) and melatonin), probiotic modulation (via gut-brain axis (GBA) regulation), and precision therapies (such as mesenchymal stem cells (MSCs) and exosome-based approaches)

Neurotherapeutics 13, 833843

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Zn deficiency has been associated with increased expression of inflammatory factors in the pathogenesis of oesophageal cancer (Reference Taccioli, Chen and Jiang136) , a process that can be reversed with supplementation (Reference Ma, Li and Fang137)

A: Products with mild actives (e.g., niacinamide, vitamin C) are generally safe for ongoing use