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doi: 10.1515/jpm-2013-0175

R 1 can be selected from the group consisting of H, a polymer derived from polyethylene glycol with a molecular weight comprised between 200 and 35000 Daltons and R 5 CO, wherein R 6 is selected from the group consisting of C 1 -C 24 alkyl, C 2 -C 24 alkenyl, C 2 -C 24 alkynyl, C 3 -C 24 cycloalkyl, C 5 -C 24 cycloalkenyl, C 8 -C 24 cycloalkynyl, C 6 -C 30 aryl, C 7 -C 24 aralkyl, 3-10 membered heterocyclyl ring, and a heteroarylalkyl containing from 2 to 24 carbon atoms and from 1 to 3 heteroatoms, wherein the alkyl group has 1 to 6 carbon atoms

over 70).[ref] Supplemental L-carnitine: L-carnitine and acetyl-L-carnitine are readily available as supplements and may be beneficial for someone with carnitine-related genetic variants

Cardiovascular disease In the studies discussed below it is important to note that treatment with L-carnitine or propionyl-L-carnitine was used as an adjunct (in addition) to appropriate medical therapy, not in place of it

Medium-chain acyl-carnitines were shown to be lower as the severity of NAFLD worsened (Enooku et al., 2019)