si-RNA, small interfering RNA
When compared to matched normal thyroid tissue, both benign (human follicular adenomas, or FTAs) and malignant (follicular (FTC) and papillary thyroid carcinoma (PTC)) lesions were found to have elevated nuclear levels of 8-oxo-dG (118) which most likely reflects the detrimental effects of prolonged exposure to chronic OxS seen during thyroid cancer (113, 118)
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ARLD: alcohol-related liver disease BAs: bile acids CL: cardiolipin Cyt C: cytochrome c DAMPs: danger-associated molecular patterns Drp-1: dynamin-related protein 1 ER: endoplasmic reticulum ETC: electron transport chain FA: fatty acid FFA: free fatty acids GPX: glutathione peroxidase GSH: glutathione H 2 O 2 : hydrogen peroxide HCC: hepatocellular carcinoma HSCs: hepatic stellate cells IL: interleukin IMM: inner mitochondrial membrane IRF: interferon regulatory factor KCs: Kupffer cells MAMs: mitochondrial-associated membranes MASH: metabolic-associated steatohepatitis MASLD: metabolic dysfunction-associated steatotic liver disease MAT1A: methionine adenosyltransferase 1A mChol: mitochondrial cholesterol mGSH: mitochondrial glutathione mtDNA: mitochondrial DNA NLRP3: NLR family pyrin domain containing 3 O 2 : molecular oxygen O 2 : superoxide anion OMM: outer mitochondrial membrane OXPHOS: oxidative phosphorylation PC: phosphatidylcholine PE: phosphatidylethanolamine PGC-1: peroxisome proliferator-activated receptor gamma co-activator 1 Prx: peroxiredoxins PS: phosphatidylserine ROS: reactive oxygen species SAM: S -adenosylmethionine carrier STARD1: steroidogenic acute regulatory protein TG: triglycerides Trx: thioredoxin Cartoons in Figures were created with BioRender.com

The use of the nutraceutical PROFERTIL a dietary management of the male factor, for the improvement of semen quality, EAU, Annual meeting, Abstract, Bratislava, Oct 2010