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doi: 10.1016/j.fm.2014.03.023 58 Ruiz-BarbaJ

We found that SHED-CM treatment upregulated the gene expression of several antioxidant enzymes such as sod , cat , hmox1 , and nqo1 in both mouse SG and human acinar cell lines after irradiation

These animal studies showed dose-dependent increases in GH pulsatile secretion, elevated mean GH levels, and resulting physiological effects including enhanced growth rates, increased lean body mass, and reduced adiposity

Cancer Res 2017;77:14761484

In addition, circular RNA inhibits ferroptosis by inhibiting miR-874-3p and regulating gene expression of related transmembrane proteins such as glycerophosphodiester phosphodiesterase 2 [144]