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Taken together, SsCm1 promotes infection by targeting the chloroplast development related protein MORF2s, which functions as a negative regulatory factor for basic immunity and resistance to pathogens

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The initial colonization of CRC tissues is facilitated by extracellular vesicles derived from F.n (FnEVs), which transfer the outer membrane protein FomA to cancer cells, creating a niche for bacterial adhesion and aggregation (Zheng et al., 2024)

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It would be of interest to examine the compensatory structural rearrangements that have occurred in Plasmodium GS to accommodate this insert and their impact on GS activity

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To address this, advanced modeling strategies based on human single-cell and spatial transcriptomics are neededsuch as human skin organoids, ex vivo skin explants, or fully immunocompetent humanized mouse modelsto dissect the true functional landscape of Vitamin D within complex signaling networks

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