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Available from, as of March 27, 2018: Escitalopram, like other selective serotonin re-uptake inhibitors, enhances serotonergic activity by binding to the orthosteric (i.e

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Abnormal expression or altered function of glutamate receptors and changes in the subunit composition of the receptors lead to increased sensitivity of neurons to glutamate, prompting the release of more glutamate [16,17,18]

The chosen substrates were selective for the respective human CYP isoforms