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The lack of standardized methods to evaluate total antioxidant capacity and the oxidation state and the use of inadequate antioxidants and/or improper concentrations of antioxidants lead to failure of numerous clinical trials directed to prevent or mitigate progression of atherosclerosis (230233)

Vitamin C or ascorbic acid reacts with singlet oxygen ( 1 O 2 ), peroxyl radical (ROO), hydrogen peroxide (H 2 O 2 ), and hydroxyl radical (OH), to form the dehydroascorbate A) and semidehydroascorbate radical (A) as shown in equation below (Phaniendra et al., 2015)

10 Endogenous antioxidants are the antioxidants made by the human body, while exogenous antioxidants are obtained through a persons diet by supplementation

Contribution of mitochondrial GSH transport to matrix GSH status and colonic epithelial cell apoptosis

Du Y, Xia L, Jo A, Davis RM, Bissel P, Ehrich MF, et al