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Gibco TM , Thermo Fisher Scientific, Netherlands # A2858501) at 37 C, 5% CO 2

doi: 10.3390/ijms24087318 141

Blockade of lactate dehydrogenase-A (LDH-A) improves efficacy of anti-programmed cell death-1 (PD-1) therapy in melanoma

Excitingly, EGCG inhibited IFN - - induced phosphorylation activation of JAK2, STAT1 and STAT3 in human melanocytes and significantly suppressed the levels of ICAM-1, CXCL10 and MCP-1 in a dose-dependent manner