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Fracture Risk: Low B12 levels are clinically linked to higher homocysteine, which weakens the bone matrix and doubles fracture risk in seniors

Elevated homocysteine can also interfere with nitric oxide signaling and vascular function, impacting overall cellular homeostasis

Shu-Bing Qian, Ph.D

Panahi Y, Saadat A, Beiraghdar F, Sahebkar A (2014) Adjuvant therapy with bioavailability-boosted curcuminoids suppresses systemic inflammation and improves quality of life in patients with solid tumors: a randomized double-blind placebo-controlled trial