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If hyperdiuresis is attempted, it must be monitored carefully and discontinued if patients don't respond favorably

CSF examination also shows elevated lactate levels in addition to low homovanillic acid (HVA), along with high levels of 3-O-methyldopa, levodopa, and 5-hydroxytryptophan, suggesting the dysfunction of aromatic L-amino acid decarboxylase (AADC)

Cold water dramatically slows dissolution

Response: We acknowledge comments that cited the additional burden to calculate the count of allowed amounts used when calculating the median, 10th percentile, and 90th percentile allowed amounts, derived from EDI 835 ERA transaction data