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Additionally, emerging evidence suggests that chronic systemic oxidative stress, inflammation, and insulin resistance contribute to neuroinflammation and neuronal damage, increasing the risk of Alzheimers disease (Patel and Edison 2024)

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Electroporation buffer and unloaded RFP were removed by ultrafiltration via an Amicon centrifugal filter (Millipore, UFC510096, 100 kDa molecular weight cutoff) followed by three washes with DPBS buffer (10 mM, pH 7.4, 13,000 g) at 4 C

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Finally, behavioral coaching informed by personal data helped participants to improve clinical biomarkers