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The following sections will systematically dissect this cycle in terms of its mechanistic basis and pathological consequences

We chose to use the term cytokine storm secondary to COVID-19

10.1016/S0165-6147(02)02086-2 Trends Pharmacol

The models crucial feature is that selectin-carbohydrate, chemoattractant-receptor, and integrin-immunoglobulin interactions act sequentially rather than in parallel