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In addition to these effects, NAC has been shown to inhibit the expression of pro-inflammatory cytokines and inducible nitric oxide synthase, reduce serum lipid peroxidation, and restore non-enzymatic antioxidant defences (Kasperczyk et al., 2014

RSL3 was first dissolved in DMSO, then diluted in M2 medium to achieve a final concentration of 5 M 32

It has been reported that MOTS-c improves age-related insulin resistance in male mice by increasing glucose intake in soleus muscles (20)

Ligand structures were cleaned using gradient optimisation after adding explicit H-atoms using Marvin Sketch 5.0.7 software

These recent findings build upon decades of foundational research into enzyme therapy and its role in modulating inflammatory pathways