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Further screening of the effects of several histone methyltransferase inhibitors on ferroptosis revealed that BRD4770, an inhibitor of H3K9me1/2/3, significantly inhibited ferroptosis in HASMCs, and its effect was comparable to that of Fer-1, a classical ferroptosis inhibitor

Gouverneur M, Berg B, Nieuwdorp M, Stroes E, Vink H

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Increased delivery of NEFA to the liver leads to hepatic steatosis, and facilitate alcohol-induced liver injury by activating KCs [215]