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Consequently, GPX4 activity decreases, reducing cellular antioxidant capacity, leading to lipid peroxidation accumulation and inducing oxidative cell death, known as ferroptosis

One of the best-known examples of plants with increased -carotene content is Golden Rice, created through the simultaneous overexpression of the narcissus gene encoding PSY (Figure 2) and a bacterial carotene desaturase [121]

The deficiency of taurine in mice results in anomalous bipolar cell plasticity and retinal ganglion cell loss [150]

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EETs are further metabolized by epoxide hydrolases (EHS) to dihydroxyeicosatrienoic acids (DHETs) [44, 138]