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showed that in the emergency department, the circulating concentration of syndecan-1, a marker of glycocalyx degradation, correlates with the fluid requirement, severity of sepsis, extent of organ dysfunction, and risk of mortality, but a direct relationship with glycocalyx degradation has not been identified (123)

Joint and Tendon Protection: BPC-157 has been shown to enhance the healing of tendons and ligaments, making it particularly beneficial for individuals with joint pain or those recovering from joint injuries

Response: We thank commenters for their thoughtful feedback on the requests for information and note that we will take these comments into consideration for the future

suggests that BPC-157 may also interact with inflammatory signaling, specifically by attenuating inflammatory cell infiltration in research models