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The NLRP3 complex promotes the cleavage of pro-caspase-1 into active caspase-1, facilitating the maturation and release of IL-1 and IL-18, amplifying inflammation and pyroptosis within the ovarian microenvironment (Yin et al

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In general, GWAS suggest that both bipolar I disorder and schizophrenia are characterized by polygenic inheritance, such that many common variants, each with a very small effect size, contribute to the disorders (23, 24)