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Cyto-C on the cytoplasm further activate caspase 9, which in turn triggers caspase 3 to initiate apoptosis [42]

Wang W, Pan H, Ren F, Chen H, Ren P

PubMed , JCI Insight , vol

In M, Richardson KC, Loewa A, Hedtrich S, Kaessmeyer S, Plendl J

reported that the inactivation or loss of ACSL4 makes the long-chain PUFA tails more likely to be converted to short-chain and monounsaturated fatty acyl (MUFA) tails, lowering the propensity to succumb to ferroptosis [56]