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Caspase 3 activity assay Fifty milligrams of frozen remnants livers were lysed in caspase 3 activity buffer (20 mM PIPES, 100 mM NaCl, 10 mM DTT, 1 mM EDTA, 0.1% CHAPS, 10% sucrose, pH 7.2)

Immediate emergency care is warranted if abdominal pain reaches 7/10 severity, especially when combined with confusion, easy bruising, or swelling in the legs and abdomen indicating potential liver failure

doi: 10.1002/acr.21660 42 ParksCGHoppinJADe RoosAJCostenbaderKHAlavanjaMCSandlerDP

Statistical analysis was conducted using the GraphPad software v.5.0 (La Jolla, CA, USA)

CrossRef GLP-1 Receptor Agonists in Mood Disorders: A Psychiatric Perspective Pietro Carmellini, Alessandro Cuomo, Maria Beatrice Rescalli, Andrea Fagiolini Life.2025