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Targeted inhibition of NNMT improves insulin responsiveness and may protect against diet-induced obesity. Hong et al., Nature Medicine Longevity and Anti-Aging Potential Because NAD is vital for DNA repair, circadian rhythm regulation, and mitochondrial health, 5-Amino-1MQ is being explored as a geroprotective agent especially when stacked with NAD boosters or sirtuin activators

Plant Physiol 140:613623 Smeets K, Opdenakker K, Remans T, van Sanden S, van Belleghem F, Semane B, Horemans N, Guisez Y, Vangronsveld J, Cuypers A (2009) Oxidative stress-related responses at transcriptional and enzymatic levels after exposure to Cd or Cu in a multipollution context

DOI:10.1084/jem.151.2.328 92

doi: 10.1016/j.freeradbiomed.2023.05.027 34 De VitaSBoiocchiMSorrentinoDCarboneAAvelliniCDolcettiRet al

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