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With the development of highly sensitive techniques based on mass spectrometry to determine acylcarnitine profiles in blood, urine or dried blood spots (DBS), a fast screening method for lcFAOD has become available [34, 35]

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Therefore, dietary intervention possibly upsets the production of TMAO by changing the composition ratio of the intestinal flora

Due to the lack of reports of adverse effects when the Dietary Reference Intakes (DRI) for pantothenic acid were established in 1998, the Food and Nutrition Board of the Institute of Medicine (now the National Academy of Medicine) did not establish a tolerable upper intake level (UL) for pantothenic acid (22)

( b ) Same as (a), but S-phase was assessed by BrdU incorporation (n = 3 technical replicates representative from 2 independent experiments)