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These proteins undergo minimal turnover as the lens ages

Exercise-induced mitochondrial biogenesis begins before the increase in muscle PGC-1alpha expression

Changes in the oxidation of biomolecules can be found in many human diseases of the body, but the cataract is one of the most common diseases, where oxidative modifications of proteins 5 and lipids 1,2 is a dominant metabolic substrate of pathological disorders

And with our hectic lifestyle involving frequent exposure to UV rays, pollution, and stress, treating it becomes even more challenging

Summary and future direction The inability of a medication to cross the BBB to achieve an effective therapeutic concentration in the brain has been the major cause of treatment failure for many brain diseases