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CL polysaccharides can significantly extend the swimming time of mice, potentially by inhibiting the levels of inflammatory factors such as TNF- and IL-6, thereby enhancing immunity and reducing oxidative stress through increased SOD activity (77)

Regardless of these events, gut-derived inflammation may also activate TLR and intracellular signaling pathways like NFB, p38, and MAP kinase, coordinating the expression of inflammatory genes [21]

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