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INTERLEUKINS, MACROPHAGES, KERATINOCYTES, ENDOTHELIAL CELLS, LYMPHOCYTES, FIBROBLASTS, OSTEOBLASTS, BASOPHILS, MAST CELLS: Activates fibroblast differentiation

Huang W, et al

A reduction in detoxification activity occurs when the deletion in gene GSTM1 is inherited, meaning that being a homozygous carrier of a deletion in the GSTM1 gene causes a reduction in enzyme activity