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Fluorescent dyes used to measure m are lipophilic, cationic compounds that cross the mitochondrial outer and inner membranes and accumulate in the matrix based on its negative charge (121)

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This effect is achieved mainly through the suppression of the levels of NLRP3, cleaved caspase-1, cleaved IL-1 and cleaved IL-18 and the pyroptosis-related protein gasdermin D N-terminal domain (GSDMD-N) induced by MI