It is thought that the secondary pathway by which AOD9604 causes fat loss, the pathway that is independent of beta-3-adrenergic receptor activation, may play a role in improving metabolic metrics even while it boosts fat loss- AOD9604 exhibits minimal side effects, high oral and excellent subcutaneous bioavailability in mice
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Practitioners who work with AOD-9604 do so under research-use frameworks, and the evidence base for efficacy, while mechanistically interesting, did not survive the Phase IIb primary endpoint test
If you already feel confident administering GLP-1 injections, discuss with your provider whether a SubQ B12 or NAD+ injection could fit into your personalized wellness plan
[1] [2] Studies have found that correcting B12 deficiency can lead to improvement in ulcer frequency and severity in affected patients