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Individuals deficient in glucose-6-phosphate dehydrogenase (G6PD) are at great risk from sodium nitrite therapy because of the likelihood of severe haemolysis, but the risk from amyl nitrite is likely to be less because only low plasma concentrations are achieved

## **Documentation requirements for J2350** As with any procedure, especially involving injecting drugs into patients, it's important to document the following before you file for a claim that includes this code: - The full name of the personnel who administered the injection + their credentials - The name and address of the facility where the injection was administered - The physician's order for this injection - The full name of the patient - The date and time of the drug administration by injection, including the NDC number of the injection - Patient records showing they have been diagnosed with a type of multiple sclerosis (e.g., primary progressive MS, relapse-remitting MS, etc.) - Patient records showing any other active disease - Patient records showing if they have an active infection - Patient records showing if the patient had clinical relapses of MS - Hepatitis B virus screening results (if this is the first dose

We provide several medication options should that be a part of your treatment plan
Key implementation steps for researchers include: establishing proper laboratory infrastructure, developing comprehensive safety protocols, implementing quality control measures, and maintaining detailed documentation throughout the research process