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Description

Vascular complications of severe hyperhomocysteinemia in patients with homocystinuria due to cystathionine beta-synthase deficiency: Effects of homocysteine-lowering therapy

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WoE analysis Evidence Assessment Responseresponse and incidence concordance Toxicity mediated by redox cycling is based on acceptance of an electron by a chemical from a reductant, formation of a radical, and transfer of an electron to molecular oxygen

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Additionally, the high expression of GPX3 may be related to the immunosuppressive state of the TME, with its expression positively associated with plasma cells and M0 macrophages and negatively associated with monocytes and M1 and M2 macrophages (Fig

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