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Mucosal surfaces can be colonized by commensals that provide benefits to the host by providing nutrients or protection from pathogens [90]

Coffee is extremely complex, and various beneficial compounds can be created and destroyed at different roast levels

Microbial regulation of the L-cell tanscriptome

A 2015 Cell Metabolism study that first characterized MOTS-c as a mitochondria-derived regulator of metabolic homeostasis capable of reducing obesity and insulin resistance in animal models was foundational in establishing this peptide class

The authors also acknowledge financial support from UGC-CAS doctoral fellowship (to P.P.), DST-INSPIRE fellowship (to O.M.) and CSIR-Junior research fellowship (to A.B.)