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10.31083/j.fbl2704131 201 ZengC.YangQ.ZhuM.DuL.ZhangJ.MaX.et al (2014)

7 Imaging biomarkers 7.1 Imaging markers based on ultrasound Transcranial ultrasonography, with a diagnostic sensitivity of 84% and specificity of 85%, can identify anomalies of nigral iron deposition in PD patients, which present as nigral hyperechoicity (Tao et al., 2019)